Eric Dane dies at 53 after ALS Battle: 10 things to know about the Grey’s Anatomy star
Eric Dane in June 2025. Image Credit: Frazer Harrison/Getty Images for Prime Video
Hollywood is mourning the loss of Eric Dane, the beloved actor best known for his roles in Grey’s Anatomy and Euphoria. Dane died on February 19 at age 53, nearly one year after publicly revealing his diagnosis of amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s Disease.
His family confirmed he passed away following what they described as a “courageous battle with ALS,” surrounded by loved ones. As tributes pour in from fans and colleagues, here are 10 essential things to know about the actor whose charisma and complexity left a lasting mark on television and film.
1. He Became a Household Name as Dr. Mark “McSteamy” Sloan
Dane skyrocketed to fame in 2006 when he joined Grey’s Anatomy as Dr. Mark Sloan. Initially introduced as a recurring character, overwhelming fan reaction quickly elevated him to series regular status.
His portrayal of the confident yet emotionally layered plastic surgeon earned him pop culture icon status and the unforgettable nickname “McSteamy.”
2. He Revealed His ALS Diagnosis in 2025
In 2025, Dane publicly shared that he had been diagnosed with ALS, a progressive neurodegenerative disease. Following his announcement, he became a vocal advocate for awareness and research.
His family noted that even during his illness, he remained determined to support others facing similar battles.
3. He Was Born in San Francisco
Born in 1972 in San Francisco, Dane experienced tragedy early in life. His father died when he was just seven years old, a loss he later described as devastating.
That early hardship shaped much of his emotional depth, both personally and professionally.
4. Acting Was an Unexpected Career Path
Dane initially pursued water polo in high school. However, after being cast in a stage production of All My Sons, he discovered a passion for acting that would change his life.
He later moved to Los Angeles with little money but big ambition.
5. Early TV Roles Built His Career Foundation
Before landing his breakout role, Dane appeared in guest spots on popular television shows throughout the 1990s and early 2000s, steadily building his résumé.
He also had a recurring role on Charmed before Grey’s Anatomy transformed him into a star.
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6. He Left Grey’s Anatomy in 2012
Dane exited Grey’s Anatomy in 2012 when his character was written off the show. In later interviews, he suggested he was let go rather than voluntarily leaving.
He candidly discussed personal struggles at the time, including battles with addiction, while also acknowledging the financial realities of network television decisions.
7. He Reinvented Himself on Euphoria
Years after playing a romantic lead, Dane embraced a darker, more complex role as Cal Jacobs on Euphoria. The character allowed him to explore themes of secrecy, identity, and morality.
Critics praised his layered performance, calling it a bold career reinvention.
8. He Starred in Major Films
Beyond television, Dane appeared in films such as Valentine’s Day, Marley & Me, Burlesque, and Bad Boys: Ride or Die, showcasing versatility across genres.
9. His Personal Life Made Headlines
Dane married actress Rebecca Gayheart in 2004, and the couple welcomed two daughters, Billie and Georgia. Though Gayheart filed for divorce in 2018, she later moved to dismiss the filing in 2025.
Dane had previously spoken openly about personal mistakes, addiction recovery, and mental health struggles, emphasising growth and accountability.
10. He Is Survived by His Daughters
Dane is survived by his daughters, Billie and Georgia, who his family described as “the center of his world.” His passing leaves behind not only a celebrated body of work but also a legacy of resilience and advocacy.
Eric Dane’s Legacy in Hollywood
From heartthrob surgeon to emotionally conflicted father figure, Eric Dane’s career reflected a willingness to evolve. His performances resonated with millions, while his openness about addiction and ALS demonstrated courage beyond the screen.
As tributes continue across social media, fans remember not just “McSteamy,” but a performer who embraced vulnerability, complexity, and redemption.
FAQ
How did Eric Dane die?
Eric Dane died on February 19, 2026, following a battle with ALS (amyotrophic lateral sclerosis).
When did Eric Dane announce his ALS diagnosis?
He publicly revealed his ALS diagnosis in 2025, nearly one year before his death.
What was Eric Dane best known for?
He was best known for playing Dr. Mark Sloan on Grey’s Anatomy and Cal Jacobs on Euphoria.
Why did Eric Dane leave Grey’s Anatomy?
His character was written off in 2012. Dane later said he believed he was let go, citing network and contractual reasons.
Was Eric Dane married?
Yes. He married Rebecca Gayheart in 2004. They share two daughters.
Did Eric Dane have children?
Yes, he had two daughters, Billie and Georgia.
What is ALS?
ALS, also known as Lou Gehrig’s Disease, is a progressive neurological disease that affects nerve cells controlling voluntary muscle movement.
What other movies did Eric Dane star in?
He appeared in Valentine’s Day, Marley & Me, Burlesque, The Last Ship, and Bad Boys: Ride or Die.
How old was Eric Dane when he died?
He was 53 years old.